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Old December 17th, 2018, 11:04 AM
ray7667 ray7667 is offline
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panleukopenia recovery. still throwing up after 22 days

Pablo is a 5 months old british shorthair mail. he was diagnosed with severe pnleukopenia (distemper) the first 5 days he was throwing up about 20 times a day with severe diarheoa and fever. he also lost his sense of smell in that period. after 2 weeks of iv,injections, and medical veteranary care we got him home. pablo now occasionnaly plays, he started eating (not much but its something). 3 weeks have beens and he stopped vommiting and his metabolism was good again and the fever has gone. on the 4th weeks pablo started throwing up again once a day and cant eat properly as food falls from his mouth. he purrs sometimes but preferes to sit quitly most of the time. we are really worried and would like some advice/more info about panleukopenia recovery and whether this throwing up is normal in this time of recovery. thank you in advance.
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Old December 17th, 2018, 06:16 PM
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hazelrunpack hazelrunpack is offline
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Have you talked with the vet that cared for him when he was so ill before? Probably that's the best source of info for you. I don't think a relapse this far along is normal.

Sending along healing vibes and good wishes for Pablo!
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Old December 17th, 2018, 10:52 PM
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Reg Reg is offline
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Hi ray7667;

Welcome to the forum. Hopefully we can give you some ideas that might help Pablo.

I agree with hazelrunpack on it not being a relapse, because of the time that has passed since the illness.

Would you mind supplying us with some more information on the treatment and medication Pablo was administered when he was so ill. Something else that might be of use would be the type of food he is being fed, for instant dry, canned, or species specific.

This information might trigger some ideas of what the causes with some of the other members, and help to give you something to think about.
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Old January 23rd, 2019, 10:12 PM
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Dr Lee Dr Lee is offline
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Hello, I am sorry to hear about what Pablo is going through. It is wonderful that he made it through the hospitalization. This is not always the case with cats diagnosed with panleukopenia. It can be a devastating disease.

The hallmark of panleukopenia pathology is crypt epithelial cell necrosis of the small intestines. In English, the first layer of the intestines which include the glands dies from the virus. This sloughing leads to diarrhea which is often bloody. To make matters worse, the name of the disease “panleukopenia” describes what occurs to the blood and immune system. Pan = all, leuko = white blood cell, penia = lack of. The defenses are decimated by reducing the numbers of all types of white blood cells. As a result, the cat is rendered defenseless and is at high risk for secondary infection.

The widespread inflammation and destruction of the intestinal layer is highly painful which, in part, accounts for the vomiting. As the infection resolves, the clinical signs of infection should resolve as well.

With vomiting occurs weeks after the viral infection, there are several different possibilities. There could be residual pathology and inflammation from the virus however we need to rule out other possibilities first. The virus can generate extensive damage which can lead to scarring in some cases. If the scarring is severe enough, it could lead to motility issues which cause vomiting. Depending on the situation, there may be surgical methods to correct this.

Other possibilities include secondary or primary bacterial or parasitic infections. The patient is fairly young for inflammatory bowel disease or lymphoma. However, if a biopsy to evaluate if continued viral effects exists is performed, then it would also rule these out.

My recommendation would be to recheck with your veterinarian and ask her or his opinion on next steps. Has Pablo been also dewormed, had a fecal, and a follow-up blood test? Therapeutic diets can also not only replace water-soluble vitamins, pre-biotics, and provide highly-digestible proteins but are often enriched in glutamine which help increase intestinal healing. Probiotics are also helpful. However, before you make any changes, I would consult your veterinarian and have a recheck examination.

I hope that this helps clarify the background biology of this condition and potential sequelae. Best of luck and please let us know how Pablo is doing.
Christopher A. Lee, DVM, MPH, Diplomate ACVPM
Preventive Medicine Specialist With a Focus on Immunology and Infectious Disease
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Old January 24th, 2019, 10:29 AM
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marko marko is offline
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Thanks for the info. Dr. Lee - Great to hear from you
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