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  #1  
Old February 3rd, 2009, 12:32 PM
Milly Milly is offline
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Anti biotic treatment for canine oral papilloma??

Hi there,
I posted a couple of days ago about my puppies warts. She has a lot of them, about 20 and they seem to be growing a bit, but not to the point that it's causing her any difficulty.

My vet initially said to just wait it out. I called her daycare and they said their vet recommends Varalyis. I called my Vet, she did some research and disagreed with the Varylis. She recommended an anti-biotic (as with people don't most Dr's say that anti biotics don't work for viruses??). I've done so much research and can't seem to find much about warts and antibiotics. I keep seeing things on message boards about l lysine? But am not sure about the dosage for a 35 pound puppy? Any suggestions?

I know they are not life and death, but I think we should keep her out of daycare until they subside and we all love that she can go there. It poops her out, we get a day a week that we don't need to run home and let her out. Also, you just never know when/if we'll need to board her and we'd hate to lose that as an option for a few months.

Any suggestions?? Thanks SO much in advance!
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  #2  
Old February 25th, 2009, 10:27 AM
Milly Milly is offline
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update

Well I guess no one else had experience with this either!!

I thought I should write back with an update just in case anyone else happened upon this thread hoping to find information. We did end up trying the antibiotic. It was a 10 day course of Azithromycin (not sure what the dosage was, I had to give her half a pill for 10 days). Cost was about $25.

The day after the antibiotics were finished the warts started to shrink. Over the next few days they pretty much disappeared. I know that the warts go away on their own over time anyway, so I am not 100% sure if it was time or the medication? However, she had about 20 warts (some were pretty big!)and we're pretty pleased they went away so quickly (i'd read that they can take up to 5 months to go away on their own).

Take care everyone!
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  #3  
Old February 25th, 2009, 10:38 AM
Chris21711 Chris21711 is offline
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That is great news . Unusual that you did not receive any responses to your initial post, I'm guessing it slipped off the radar
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Old February 25th, 2009, 03:25 PM
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hazelrunpack hazelrunpack is offline
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Interesting that the antibiotic worked!

I'm glad you updated! It's always good to get information on good outcomes.

I saw your post but had no experience with papillomas, so didn't reply.
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Old February 25th, 2009, 08:46 PM
Milly Milly is offline
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Hi Chris and Hazel,
No worries, I had trouble finding info re antibiotics and warts so I just assumed no one else knew either!

I'll be curious to hear if anyone else decides to try this course of treatment and how it goes. I'm just glad she doesn't have them anymore!
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Old February 25th, 2009, 10:07 PM
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Dr Lee Dr Lee is offline
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Quote:
Originally Posted by Milly View Post
Hi there,
I posted a couple of days ago about my puppies warts. She has a lot of them, about 20 and they seem to be growing a bit, but not to the point that it's causing her any difficulty.

My vet initially said to just wait it out. I called her daycare and they said their vet recommends Varalyis. I called my Vet, she did some research and disagreed with the Varylis. She recommended an anti-biotic (as with people don't most Dr's say that anti biotics don't work for viruses??). I've done so much research and can't seem to find much about warts and antibiotics.
I want to thank for your confusion with an antibioitc to treat a virus! You are correct. Anti-Bioitcs are for bacteria and Anti-Virals are for viruses and Anti-Fungals are for fungi, etc...

While Viralys (L-lysine) is an antiviral, it is typically effective for herpes virus, not papilloma. But as lysine is an amino acid and is virtually free of side effects - it probably won't hurt. However there is no evidence that I am aware of, that lysine has a positive effect on papillomas.

Typical treatment for papillomas: "a tincture of time" as my professor used to say. They generally will regress on their own, once the body's immune system responds to the virus.

Another treatment is Aldara (imiquimod). It is anti-viral treatment for genital warts in people. Here is a weblink: Aldara. I have had good success with this medication for persistent papilloma warts.

If your vet questions this - have them type in "aldara" and "papilloma" in the vin website ( VIN ) search. It will support this medication.

Best of luck!
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Old February 26th, 2009, 08:55 PM
Etown_Chick Etown_Chick is offline
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Thanks all, esp Dr Lee.
Scruffy has this. I"d heard they go away on their own so we are waiting them out. It's not bugging him, but it's good to know there options if it gets worse.
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Old March 25th, 2009, 02:29 PM
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I was sent an email by a Dr Anna McDole who found that there is an antibiotic that has been shown to effectively treat papilloma warts. It is azithromycin (Zithromax). I do not know the mechanism of action however there are several antibiotics that will have immune modulating effects as well. Perhaps azithromycin is one of them. When I find this information I will post it.

Thank you Dr McDole for the correction and I hope this information may help.
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  #9  
Old March 29th, 2009, 06:22 PM
Milly Milly is offline
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Hi Dr. Lee,
Thanks for your update! Azithromycin is the anti biotic that we ended up using for Milly. It seemed to work and we were quite pleased! So, if any of you happened upon this post while looking for puppy wart treatment I'd suggest you give this a try!
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Old March 29th, 2009, 06:43 PM
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rainbow rainbow is offline
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I have never had any experience with oral papilloma but just wanted to thank both Milly and Dr. Lee for the informative information and keeping this thread alive as it is sure to help someone else in the future.
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  #11  
Old November 27th, 2011, 10:07 PM
jmarban jmarban is offline
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Papilloma oral canine

Quote:
Originally Posted by Dr Lee View Post
I was sent an email by a Dr Anna McDole who found that there is an antibiotic that has been shown to effectively treat papilloma warts. It is azithromycin (Zithromax). I do not know the mechanism of action however there are several antibiotics that will have immune modulating effects as well. Perhaps azithromycin is one of them. When I find this information I will post it.

Thank you Dr McDole for the correction and I hope this information may help.
Dear Dr Lee:

I am writing to you in reference of the Papilloma Oral Canine, my puppy got it and My Vets and I we are trying to find how to treat this infection, we are from Venezuela, and its a rare case. I read about the use of AZITHROMYCIN, and we are very interesting on what you know about how to use this treatment.

We are very greatfuly of any information you can provided us.

Jorge Marban
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  #12  
Old June 26th, 2009, 06:40 PM
mzpatti mzpatti is offline
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Papillomas or mouth warts.

I currently foster 5 rescue dogs for 3 different groups. Rocco a 8 y/o boston terrier came down with the papilloma virus 2 months ago. This is how they looked when first discovered.


He was on medication that suppressed his immune system to treat pemphigus. Well the poor boy had no reserves to fight off this virus. Within 2 weeks they had grown to this size.
http://i362.photobucket.com/albums/o...cco/pic005.jpg They showed even with his mouth shut. We started him on Azithromycin 250 mg 1 /2 a pill for 14 days. It did nothing and by now they were enormous. The sides of his tongue and the roof of his mouth were cover in warts.
[IMG][MIG][/IMG][/IMG]
http://i362.photobucket.com/albums/o...occo/Jun16.jpg

Back he went to the vets and was given another 14 day supply. I'd really lost hope and now 2 of my other foster dogs had them.
[IMG][/IMG]
Well after an additional 10 days I started to notice they were no longer hanging out of his lip. It seemed like over night they were disappearing. I'll post photos later.
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