Neoplasene

[jackieoscar2000]

Has anyone used Neoplasene on their pet as a treatment for cancer? Please let me know asap.
THanks,
Jackie

[3dogngt]

I just started using it this week. My vet uses it frequently with wonderful results. I'd like to know how others have done.

[Hunter's_owner]

There is another post a;ready discussing this. You may want to check that one out as well.
http://www.pets.ca/forum/showthread.php?t=39807

[Frenchy]

Originally Posted by Hunter's_owner

There is another post a;ready discussing this. You may want to check that one out as well.
http://www.pets.ca/forum/showthread.php?t=39807

You might want to try this thread instead.

[carolyntb]

Hello:

I am currently using the Buck Root Suave for my 14 yr old dog with a hemangiopericytoma on her left rear leg. We had to put some needle points in to the tumor to facilitate the suave. I have been on this for over 6 weeks, applying the suave once a week. There have been many changes, lots of swelling, bleeding, oozing and such. Very messy, very uncomfortable and smelly. The tumor has huge scabs on it and every time a small piece falls off there is bleeding. I am getting a little discouraged because I do not notice the tumor becoming any smaller. I am under a vet's supervision who says that each treatment they do if different. She says to continue with it, but I may hold off for an extra week to let some healing begin. My vet does not cover the area with the suave like it says in Dr. Fox's clinical studies. Does anyone have any good news for me about this? It's so red and swollen and ugly most of the time. Does everyone cover the suave with a bandage when it's applied? Any info would be greatly appreciated.

Carolyn

[miraclemeg]

I notice that your question was asked several weeks ago so I don't know how you decided to proceed with treatment. I can tell you our experience with neoplasene and I would recommend that you continue with the treatment. Our greyhound was diagnosed with an agressive form of this same cancer on her shoulder in October. Our vet put her on both an oral dose as well as the salve. We administered the salve once a week and each time it was obvious that it caused discomfort. We also saw the scabs, which she would pull off in a day or so, bleeding, oozing, etc...

The area became an open wound and we had no idea how big it would get or how long it would take before we could stop the treatments. Early in January the vet thought the tissue he was seeing looked healthy so he kept her on the oral dose but we stopped the topical. The area has since completely healed over and we think she is cancer free - the vet took a look a couple of days ago and thought so too. We keep an eye on it and take her back in 3 months. She has been off everything for about 2 months now.

One thing you might ask your vet about is injecting the site. We did not need this, but our vet told us about several cases where he injected the tumor directly and it worked great. This has truly been a miracle for our dog, since the original pathology report did not paint a very hopeful picture for her. I think we caught it early, though, and it had not spread as far as it could have.

Best of luck.

Originally Posted by carolyntb

Hello:

I am currently using the Buck Root Suave for my 14 yr old dog with a hemangiopericytoma on her left rear leg. We had to put some needle points in to the tumor to facilitate the suave. I have been on this for over 6 weeks, applying the suave once a week. There have been many changes, lots of swelling, bleeding, oozing and such. Very messy, very uncomfortable and smelly. The tumor has huge scabs on it and every time a small piece falls off there is bleeding. I am getting a little discouraged because I do not notice the tumor becoming any smaller. I am under a vet's supervision who says that each treatment they do if different. She says to continue with it, but I may hold off for an extra week to let some healing begin. My vet does not cover the area with the suave like it says in Dr. Fox's clinical studies. Does anyone have any good news for me about this? It's so red and swollen and ugly most of the time. Does everyone cover the suave with a bandage when it's applied? Any info would be greatly appreciated.

Carolyn

[carolyntb]

Thanks for the reply. I don't see many posts on dogs with this kind of cancer (hemangiopericytoma). The area where the scabs have fallen off are very pink and healthy looking, but there are other areas where we have not even touched yet, due to the size. I am going to see my vet on Wednesday and will ask about the injections. This may be the only way to go since it only seems to be affecting the top area of the tumor and not getting into the root of the thing.

Regards,
Carolyn

[squeekymom]

Just wondering if you persued the injectable? I am dealing with fibrosarcoma in a cat and yesterday we did the injectable neoplasene...just wondering what to expect.

[Maddies-Dad]

This thread is old, but I thought I'd post to add some more information.

Our dog Madison is a 7-8 yrs old mixed breed. Approximately 45 lbs. We didn't identify the bump on her hip as an issue for awhile because she had knee surgery last year and the bump was on the non-operated on leg. We assumed it was muscle and that the other side had atrophied because of the surgery. We finally asked a vet about physical therapy to correct the muscle imbalance and was told that it was a tumor, not muscle. A biopsy confirmed that it was a cancerous tumor: Spindle Cell Sarcoma.

We began treatment of Madison's sarcoma with Neoplasene X (injectable) 6 days ago. The tumor was about 4" x 3" in size at the time with probably about 1/2 above and half below the skin level. It had been stable 3" x 2" for awhile, but had grown quite a bit after the biopsy was done a month ago.

Our vet has used the Neoplasene numerous times, but this would be the largest tumor that he has treated with it. We decided to start with injectable and then followup with topical or injectable as appropriate depending on how things were going and then oral as aftercare to destroy any tumor cells that remained.

Our vet did 7 total injections around the perimeter of the tumor and deep into the center. Maddie was quite agitated and in some discomfort for around 18 hours after the treatment. This was despite the Buprenex injection given concurrently with the Neoplasene and the Tramadol administered at home.

The next day there was a general greying of the tumor site. A reddish ring could be seen on the edge of the greying section and as the day progressed the site started blackening. The most pronounced change was around the biopsy site which was much darker than the surrounding tissue. We kept the site bandaged, but at this time there was no discharge.

Day 2 we awoke to find 2 dime sized holes in her skin and some oozing of pussy, bloody material into the bandages. Maddie did not seem to be suffering any discomfort and we had discontinued the Tramadol the previous day. There was not too much discharge and we changed the bandage 2x over the course of the day (morning and evening) cleaning with Hydrogen Peroxide and applying Buck Mountain's Wound Balm (Yarrow, Echinacea, and other stuff I can't remember).

Day 3 there was an island of blackened skin surrounded by a ring of broken skin where the tumor seemed to be eating away forming a small "moat". Despite the greater area exposed, the rate of discharge did not seem to increase that dramatically; 2 bandage changes was still sufficient.

Day 4, the rate of change seemed to have slowed with not much additional increase in the exposed area. It did appear that the edges of exposed skin were dying at a slower rate than the tumor underneath creating a "flap" that we were careful to clean under during bandage changes. A second treatment of Neoplasene was done. This time topical using the salve.

Maddie was much more agitated this time, even using higher dosages of pain medications. I assume it was because of the exposure of the salve to the bare flesh/tumor. The vet said to leave the salve on under a bandage for 24 hours. I looked at the clinical guide from Buck Mountain Botanical's website and it recommended 12 hours before cleaning the salve off. We couldn't take the whimpering and crying so cleaned the area after 10 hours. She was crying so much that we tried to be gentle and found later that we didn't do the best job removing everything; we noticed the next morning (day 5) a little of the salve was left in a couple places under the "flaps" I mentioned earlier.

Day 5 seemed to start the process over again, or maybe just kick start things a little, with more areas turning both grey and blacker. Discharge seemed to be happening still at about the same rate. I forgot to put the e-collar on her before showering and found the bandage ripped off and part of the scab and another small bit (~1/4") of tumor that was starting to fall off had been chewed off in one area. On the plus side she managed to remove all remnants of the salve which we were afraid would have been too painful if we scrubbed it ourselves. As the day progressed the rate of discharge increased and day 5 was the first 3x bandage change (not counting the extra needed for when she ripped it off).

Today is Day 6. The rate of discharge is still high. Today probably will be 4x bandage changes. The lower part of the tumor is almost all gone (with still a flap of skin over the cavity left), areas of the flap are starting to separate and fall off. The main center part of the tumor (the island in the moat), while turning black is still there as well as the top edge of the tumor (top when she's standing and looking at the tumor from the side. maybe a 1/2-3/4" wide band). It looks like another application may be needed . . .

Tomorrow we go back to the vet for the 3rd application. I am going to ask that it be injected again rather than applied to the raw flesh. It seemed to be less painful for Maddie.

You need to be prepared for a high degree of grossness. And the larger the tumor, the larger an open wound you will have to manage, both during the stage where the necrotic tissue is being destroyed as well as after when the would site is healing. My girlfriend was not as prepared and this week has been extremely stressful for her watching the size of the wound grow as well as the pain little Maddie is in after each administration of Neoplasene. I am amazed at the progress so far and have high hopes for a successful treatment.

I hope that this is helpful in terms of what you can expect, especially with a tumor on the larger side of things. I will provide more updates as time progresses.

[liltraveler]

hi. the posts on this site seem to be pretty dated, but thought i'd share my experience so far with neoplasene.

my 3 y.o. pug was diagnosed with a mast cell tumor on his stomach. surgery was an option, but i decided to try the more holistic approach. they injected my dog's tumor and within 48 hours, his tumor fell off, leaving a gaping hole. it was pretty disgusting, to be honest, but fortunately, my vet had warned me. the other problem was that it was difficult to manage the wound b/c i work (and there was no one at home to care for him). that said, the wound healed very quickly with the wound balm. it was really bad the first 4-5 days, but within a week to 10 days, the wound was nearly entirely gone.

he's now on a regimen of 1 cc/day of the oral neoplasene. he hasn't had any problems with nausea or anything--i add it to his dry kibble. though, i've heard from others that some dogs

it's a commitment--once they start on the oral neoplasene, it's a lifetime commitment (i wasn't aware of this when i decided to go this route) and it's pretty expensive (about $250/bottle, which lasts about 5 months).

the founder is a bit of a jerk. i called him because i was worried about managing the wound, and he basically screamed at me that i wasn't doing things "right," even though i tried to explain to him my situation: that i live alone, i work a full time job, and that it was exceptionally difficult to bandage my dog (pugs have a very odd body shape--broad shoulders with atiny waist--so it was like putting a bandage on a big cone!) i was feeling bad enough about my poor pooch and his pain and did not appreciate being yelled at! my advice to you is have your vet call him to ask your questions!

i'm glad i did it overall. though managing the wound was difficult and it was not cheap, i still feel the recovery time was much shorter than surgery would have been and he didn't need to have radiation or chemo. and hopefully it will keep any remaining cells at bay!

good luck, and i hope this helps anyone considering this treatment.

[hazelrunpack]

Welcome to the board and thanks for the post, liltraveler. I'm so glad the treatment seems to be successful for your boy How long ago did your dog start treatment? Please keep us posted with his progress!

I've heard similar comments about the founder. The consensus seems to be that he's a bit lacking in people skills. But if the neoplasene treatment works, I guess I could put up with a little attitude.

[Frenchy]

Originally Posted by liltraveler

they injected my dog's tumor and within 48 hours, his tumor fell off, leaving a gaping hole.

Really ? Because I read that it takes more than one treatment.

was it expensive ? not the meds but the injection , and was your dog on any pain killer ? how was he feeling after the injection ? do you have any pictures ?

sorry for all the questions but , most people come in this thread and post about it but never come back to update or to show us how it worked out.

[Maddies-Dad]

Originally Posted by Frenchy

Really ? Because I read that it takes more than one treatment.

was it expensive ? not the meds but the injection , and was your dog on any pain killer ? how was he feeling after the injection ? do you have any pictures ?

sorry for all the questions but , most people come in this thread and post about it but never come back to update or to show us how it worked out.

you can see pictures of my little girl's treatment at the link i posted above (repeated here) they show the open wound so are not for the easily grossed out.

http://s26.photobucket.com/albums/c1...die/?start=all

the total treatment including 2 injections, topical treatments, oral neo, Tramadol prescriptions, vet visits and rechecks was somewhere between $1-1.5K. this was compared to the $13K the same veterinary hospital quoted for MRI ($2k), Surgery ($3k), and followup Radiation ($8k). you definitely could tell she was in pain after the injections with whining and whimpering.

my old computer crashed so i lost pictures after day 19, but we did several more topical applications directly in the wound area after these pictures were taken because our Vet said there was still some visible malignant tissue.

we also did oral Neoplasene for about 2 months. our Vet did not say it needed to be continued indefinitely.

Maddie is doing fine now. she has a quarter sized spot with no fur where the tumor used to be.

let me know if you have any other questions.

edit: i also got yelled at by Dr. Fox when i called with some questions

[hazelrunpack]

So good to hear that Maddie is doing so well! Thanks for the information and the update, Maddie's-Dad! We get so few complete stories!

[Frenchy]

Originally Posted by Maddies-Dad

you definitely could tell she was in pain after the injections with whining and whimpering.

Did the tramadol help with her pain ? How long did she seem to be in pain ?

Thank you so much for the explanations and pictures. Neoplasene is something I am very curious about , having lost 2 of my goldens to cancer , with tumors that couldn't be operated on.

the thing that makes me think twice is the pain it brings to them. And the lack of infos about the treatments. I tried to find out from the company , if they got orders from Quebec's vets , so I could talk to a vet in my area that knew about the treatment and all they said was to tell my vet to contact them. That's not the answer I was looking for.*

I'm very happy to know that Maddie is doing good !

[Maddies-Dad]

Originally Posted by Frenchy

Did the tramadol help with her pain ? How long did she seem to be in pain ?

I'm sure the tramadol helped, but even with that she was still obviously uncomfortable. For the injections it seemed to last ~12-18hrs. For the topical it seemed to last until we cleaned it off and re-bandaged the wound (10-12 hrs). Maddie was definitely a trooper through it all

[uventi]

Hello All.
Just in case it may be of use to anyone we are starting our 10 y/o blue heeler/terrier mix on Neoplasene (oral-1 ml/day+) today. I know many people are curious about this cancer treatment as we have been. Our dog Annie was diagnosed with bladder cancer at the end of January. We started her on the vet's recommended path of chemo and Deramax. Annie had 3 chemo treatments and the vet said that the tumor was growing. The tumor is inoperable; radiation is not a viable option; the vaccine and electroporation chemo may still be an option but since chemo didn't work the first 3 times we've not put this at the top of the list as options to prioritize...
We have combed through all options.
Neoplasene seems like the last option and we're just hoping that we didn't wait too long...

When we learned of Neoplasene we were intrigued but decided to give the chemo a chance. We're now wishing we would've started with Neoplasene but it is as it is at this point.

Earlier this week Annie was not eating well so we've been trying to build her appetite. The allopathic vet told us to just keep her comfortable;

Just yesterday Annie ate enough that we thought it was time to start the Neoplasene...so we started this am. We should also say that we found a holistic vet who has recommended a regimen of supportive herbs, foods, etc. This vet has also done Neoplasene and says that she's seen internal cancer cured before...she didn't give us hope but said that she's seen its effectiveness.

If it's ok we'd like to chronicle Annie's journey with Neoplasene here to help educate us and hopefully others. We are very (cautiously) hopeful that this can help!!!
We have our fingers crossed!!!
I will post only once a week with an update.
Thanks.
Kim

[hazelrunpack]

Best wishes for Annie's treatment! Will say a few prayers for her. And please do keep us updated on her progress.

[lindapalm]

I wish you and Annie lots of luck.