Typically, just like humans, they can feel if something is not right--if they're ill, they'll feel sick; if they've hurt a limb, it hurts or hitches and they move funny; if they get into something toxic, they would feel the side effects. If it's something they were born with, they may adapt to the condition because it's 'normal' for them and they've known nothing else, but if it's a condition that developed since birth, then it might be serious.
The only way to tell for sure what's going on is a vet visit.
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"We are--each of us--dying; it's how we live in the meantime that makes the difference."
"It's not what you gather, but what you scatter that tells what kind of life you have lived!"
"Be kinder than necessary, for everyone you meet is fighting some kind of battle."
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